Human illnesses caused by opisthorchis felineus flukes. Feb 06, 20 lvova mn, tangkawattana s, balthaisong s, katokhin av, mordvinov va, sripa b. A fecal sample tested positive for opisthorchis sp. Mild cases can result in abdominal pain, diarrhea, or constipation. Human illnesses caused by opisthorchis felineus flukes, italy. Opisthorchiasis is an infection caused by either of the two parasite worms, the cat liver fluke, or scientifically called opisthorchis felineus also known as opisthorchis tenuicollis, or the southeast asian liver fluke called as opisthorchis viverrini. Cryptic and asymptomatic opisthorchis felineus infections. To reduce this health burden, a comprehensive prevention and control.
What are the signs and symptoms of opisthorchiasis. The animals were sacrificed on weeks 4, 8, 12, 16, 28 and 42. Opisthorchis felineus has a complex life cycle involving three hosts. Chart and diagram slides for powerpoint beautifully designed chart and diagram s for powerpoint with visually stunning graphics and animation effects. A high prevalence has been reported in byelorussia, russia, and the ukraine. The liver fluke opisthorchis felineus as a group iii or group i. Macrophotograph of the liver of uninfected hamster control at a 5, b 24 and c 48 weeks after the start of the experiment. Infeetion with livr flukes opisthorchis viverrini, opisthorchis felineus and clonorchis sinensis 1. Apr 30, 2018 similar to bile duct cancer or cholangiocarcinoma cca in the western world, opisthorchiasisassociated cca in southeast asia is an aggressive cancer with high mortality rates. Theyll give your presentations a professional, memorable appearance the kind of sophisticated look that todays audiences expect. Pdf opisthorchis viverrini and opisthorchis felineus.
Opisthorchis felineus is a trematode that is transmitted to humans through the consumption of raw freshwater fish of the family cyprinidae. The influence of opisthorchis felineus invasion on the development of pathological changes in the hepatobiliary system was studied in 120 golden hamsters in a longterm experiment 42 weeks after single infection per os in the dose of 50 metacercariae per animal. The opisthorchis viverrini genome provides insights into life in. Oct 20, 2014 opisthorchiasis is a trematode fluke infection caused by infection with one of the species of the liver fluke opisthorchis, which is acquired by eating raw or undercooked freshwater fish containing infectious metacercariae. Clonorchis sinensis, opisthorchis viverrini and opisthorchis felineus are three closely related species that produce similar clinical manifestations in humans. The adult flukes deposit fully developed eggs that are passed in the feces. Opisthorchis viverrini an overview sciencedirect topics. Epidemiology, diagnosis and control of opisthorchis. After ingestion by a suitable snail first intermediate host, the eggs release miracidia, which undergo in the snail several developmental stages sporocysts, rediae. The liver and intestinal fishborne zoonotic trematodes flukes are important parasites of humans and animals and are estimated to infect more than 18 million people, especially in asia. Opisthorchis felineus, or cat liver fluke is a trematode parasite that infects the liver in mammals. Pdf study on the surface morphology of the developmental stages.
The liver fluke opisthorchis felineus as a group iii or. The liver fluke opisthorchis felineus as a group iii or group. The woman reported that she had consumed raw fillet of tench tinca tinca during a gastronomic event in the town of bomarzo viterbo province, latium region on december 8, 2009. It demonstrates high diagnostic and therapeutic potential. Infection with high worm burdens has high impact on health status in endemic. Opisthorchis felineus definition of opisthorchis felineus. Diagnosis of opisthorchis infection is based on microscopic identification of eggs in stool specimens. The term fluke means flatfish, since these parasites are flat. Opisthorchis species are liver fluke parasites that humans can get by eating raw or undercooked fish, crabs, or crayfish from areas in asia and europe where the parasite is found, including thailand, laos, cambodia, vietnam, germany, italy, belarus, russia, kazakhstan, and ukraine. Opisthorchiasis is a parasitic disease caused by species in the genus opisthorchis specifically, opisthorchis viverrini and opisthorchis felineus. Opisthorchis felineus opisthorchis viverrini clonorchis sinensis. Specific features of progression of the parasitic invasion. Humans become infected by eating raw or poorly cooked fish containing the larval forms.
It was first discovered in 1884 in a cats liver by sebastiano rivolta of italy. Foodborne trematodiasis and opisthorchis felineus acquired. Seasonal and spatial environmental influence on opisthorchis. To reduce this health burden, a comprehensive prevention and control program for. Opisthorchis felineus wikipedia republished wiki 2. After ingestion by a suitable snail first intermediate host, the eggs release miracidia, which undergo in the snail several developmental stages. It is also present in puerto rico and possibly other caribbean islands.
Pdf the liver fluke opisthorchis felineus is a member of the triad of epidemiologically important. Author summary opisthorchis viverrini ov is a fishborne parasite infecting humans when they consume raw or undercooked fish. In this work the formation of cocalled hemozoin knobs the bile duct ectasia filled up by hemozoin pigment in opisthorhis felineus infected hamster liver has been observed. Morphology of opisthorchis felineus pixelmasterdesign. Infection with opisthorchis viverrini and its associated cholangiocarcinoma cca is an underestimated problem in the mekong region of southeast asia, despite the widespread use of praziquantel. The eggs are shed in the biliary tree of fisheating mammals and are passed with feces. The international agency for research on cancer classifies the infection with the liver flukes opisthorchis viverrini and. They are genetically related to other opisthorchid flukes of cats, including clonorchis sinensis opisthorchis spp have been recorded frequently in russia, the ukraine and kazakhstan. Infection with opisthorchis felineus induces intraepithelial. Epidemiology of opisthorchis felineus in the european union edoardo pozio european union reference laboratory for parasites o. When present, symptoms fever, nausea, abdominal pain, and myalgias were mild. Individuals infected for a long time chronic may get serious illness.
We report 2 outbreaks of opisthorchis felineus infection caused by the consumption of tench filets tinca tinca from a lake in italy. Media in category opisthorchis felineus the following 3 files are in this category, out of 3 total. Opisthorchiasis is prevalent in western siberia and in the region of the dnieper. In 1891, russian parasitologist, konstantin nikolaevich vinogradov 18471906 found it in. Opisthorchis viverrini poirier 1886 poirier 1886 encyclopedia. The eggs are shed in the biliary tree, enter the intestine, and are passed with feces. Experimental and modelling investigations of opisthorchis. People are infected after eating raw or undercooked fish.
Transmission takes place in various environments and water habitats where many. Opisthorchis felineus opisthorchis viverrini clonorchis sinensis global estimated prevalence who, 1995. Chronic infection may lead to cholangiocarcinoma, a malignant cancer of the bile ducts. The life cycle and parasitic system of opisthorchis felineus in the. A study of tribendimidine effects in vitro and in vivo on. Opisthorchis felineus, like other trematodes, secretes two major cysteine proteases. Apr 29, 2019 opisthorchis felineus, or cat liver fluke is a trematode parasite that infects the liver in mammals. In 1891, russian parasitologist, konstantin nikolaevich vinogradov 18471906 found it in a human, and named the parasite a siberian liver fluke. More than one stool sample may be needed to detect the eggs. Most individuals infected with opisthorchiasis do not present any symptoms. Opisthorchis felineus article about opisthorchis felineus. Similar to bile duct cancer or cholangiocarcinoma cca in the western world, opisthorchiasisassociated cca in southeast asia is an aggressive cancer with high mortality rates. The liver fluke opisthorchis felineus is a member of the triad of epidemiologically relevant species of the trematode family opisthorchiidae, and the causative agent of opisthorchiasis felinea over an extensive range that spans regions of eurasia. Opisthorchosis is a helminthiasis affecting mainly the hepatobiliary system and pancreas.
Opisthorchis tenuicollis definition of opisthorchis. Opisthorchis viverrini and opisthorchis felineus, also called the southeast asian. Opisthorchis felineus infection provokes timedependent. Additionally, cysts containing the parasite can sometimes be detected by ultrasound, ct, or mri. Opisthorchis felineus rivolta, 1884 is a member of the triad of. Worldwide, the number of cases of human infection has been estimated to be 1. Trematodes flukes opisthorchis viverrini southeast asian liver fluke and opisthorchis felineus cat liver fluke. In the 1930s, helminthologist hans vogel of hamburg published an. Opisthorchiasis and clonorchiasis are zoonotic infections caused by liver flukes of the genera opisthorchis and clonorchis reported in asia and europe, where they affect an estimated 10 million people.
Health, general fish food product health aspects fish as food medical research medicine, experimental. They need to be ingested by freshwater gastropod snails, the first intermediate host, to develop into sporocysts, rediae, and free swimming cercariae, the stage infective for the second intermediate host, cyprinid fish. Liver flukes infect the liver, gallbladder, and bile duct in humans. The causative agent, the siberian liver fluke opisthorchis felineus, infests the liver, gallbladder, and pancreas of man, cats, and dogs. Opisthorchis viverrini, common name southeast asian liver fluke, is a foodborne trematode parasite from the family opisthorchiidae that infects the bile duct. Epidemiology of opisthorchis felineus in the european union. It is known to cause a significant health burden in the opisthorchiasis region in thailand and possibly throughout mainland southeast. Chromosomal disarrangement and immunoreactivity of golden. The main sources of the disease are infected persons and animals, whose feces carry the parasites eggs to water. Infection with high worm burdens has high impact on health status in endemic areas. Winner of the standing ovation award for best powerpoint templates from presentations magazine. Molecular changes in opisthorchis viverrini southeast asian liver. Opisthorchis felineus and metorchis bilis metacercariae in. Foodborne trematodiasis and opisthorchis felineus acquired in.
Pdf on jan 1, 2014, paiboon sithithaworn and others published opisthorchis viverrini and opisthorchis felineus find, read and cite all the research you need on researchgate. The eggs of opisthorchis are very similar to those of clonorchis, another liver fluke, but can be distinguished by microscopic features. Opisthorchis viverrini and opisthorchis felineus, also called the southeast asian liver fluke and cat liver fluke respectively, usually cause infections that are asymptomatic. Opisthorchiasis from imported raw fish scienceopen. Longterm infection is associated with high risk of developing cholangiocarcinoma, a generally incurable bile duct cancer type. Magnetic resonance imaging and spectroscopy for differential. They have a knob at the abopercular end that may be prominent, inconspicuous, or absent. Worlds best powerpoint templates crystalgraphics offers more powerpoint templates than anyone else in the world, with over 4 million to choose from. Infection of the definitive host follows the consumption of fish contaminated with metacercariae. Abstract opisthorchiasis caused by the liver fluke opisthorchis felineus is one of the most common helminthic infections in. Ov is endemic in southeast asia, particularly in rural parts of northeast thailand, lao pdr, cambodia and vietnam. Opisthorchis felineus is usually a parasite of cats, dogs, pigs, and whales, while opisthorchis viverrini is commonly found in dogs and cats. Infection with the parasite is called opisthorchiasis.
A parasitic system is a system in which the parasite is combined at all phases of its development. This parasite is a biliary ductdwelling trematode that can cause biliary. Opisthorchis felineus has been documented in at least 12 countries of the. Author summary opisthorchiasis caused by opisthorchis felineus is a fishborne parasitic worm infection spread in russia and some european countries. Clonorchis sinensis, opisthorchis viverrini, and o. Sep 17, 2015 hemozoin is the pigment produced by some bloodfeeding parasites. Opisthorchis felineus wikimili, the free encyclopedia. They need to be ingested by freshwater gastropod snail, the first intermediate host, to develop into sporocysts, rediae, and free swimming cercariae, the stage infective for the second intermediate host, cyprinoid fish 3, 7. Hemozoin knobs in opisthorchis felineus infected liver. Opisthorchis felineus and metorchis bilis are the main agents of. Opisthorchiasis comprises diverse clinical manifestations caused by infections with opisthorchis felineus or o. Histological analysis of the liver of uninfected hamster control.
In 1891, russian parasitologist, konstantin nikolaevich vinogradov 1847 1906 2 found it in a human, and named the parasite a siberian liver fluke. The diseases caused by fishborne liver flukes, clonorchiasis, opisthorchiasis and methorchiasis, can be severe. The causative agents of opisthorchosis are two species of liver flukes, the trematodes belonging to the family opisthorchiidae opisthorchis felineus and o. Frontiers current perspectives on opisthorchiasis control. Our new crystalgraphics chart and diagram slides for powerpoint is a collection of over impressively designed datadriven chart and editable diagram s guaranteed to impress any audience. Comparative histopathology of opisthorchis felineus and opisthorchis viverrini in a hamster model.
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